pall,颇尔,Pegasus SV4 除病毒膜式膜片,FTKSV404705, FTKSV4047025

pall,颇尔,Pegasus SV4 除病毒膜式膜片

Compact, Easily-scalable Filter Discs for Virus Removal and Small-scale Membrane Qualification Studies

Pegasus SV4 Virus Removal filters combine robust, high viral clearance of parvovirus and larger viruses with high throughput capacity and stable flowrates, in both dilute and complex concentrated biological fluids.Consistent flowrates and throughput performance provide superior control of process costs and maximizes virus filtration economy and efficiency.

Pegasus SV4 Virus Removal Membrane Filter Discs are purpose-designed for small-scale membrane qualification studies such as bacteriophage or prion (TSE agent) clearance, as well as membrane flow rate, capacity and protein transmission studies.Filter discs are lot sample tested and manufactured under a Quality Management System certified to ISO 9001:2008 in order to assure consistently high quality.


特点	优势
Pegasus SV4 virus removal filter membrane	Robust, high > 4 LRV parvovirus clearance
Constant flow and high throughput performance	Maximize virus filter process economy and efficiency
Identical membrane to larger production scale Pegasus SV4 virus filter cartridges	Offers reliable scalability
Used in 颇尔 FTK-200 disc holder	易于处理
Individual membrane box identified by lot number	Complete traceability of manufacturing history
Manufacturing lot sample tested	Assurance of consistently high quality
Membrane bacteriophage tested	Assurance of consistently high quality
Pre- and post-use installation testable	Assurance of consistently high quality at point of use
Low protein-binding	High protein recovery
Robust membrane with high viral clearance and resistance to plugging	Flow decay minimized at high virus spike concentrations and with complex or concentrated feeds

Materials

Filter fluid path components have met the specifications under Section <88> Biological Reactivity Tests in vivo listed in the current revision of the United States Pharmacopeia (USP) for Class VI plastics at 121 °C.

技术数据

材料成分


项目	Material
膜	Hydrophilic modified polyvinylidene fluoride (PVDF)
Support Disc	Polypropylene (Non-woven)
O-ring (Disc Holder)	EPDM
Disc Holder	不锈钢

孔径

20 nm (nominal)

Retention Ratings


病毒
Bacteriophage PP7	> 4 log TR*†

* Claims based on challenge with parvovirus model bacteriophage (bacterial virus) PP7

† > 4 LRV for PP7 bacteriophage per Parenteral Drug Association (PDA) TR 41 rating method for small virus-retentive filters > 4 LRV typically with mammalian parvoviruses


Effective Surface Area
11.1 cm² (1.72 in.²) in FTK-200 Disc Holder
Operating Parameters**
Recommended Temperature	4 - 45 °C
最大操作压力	5 barg (73 psig)
Maximum Differential Pressure	4.5 bard (65 psid)
Recommended Operating Differential Pressure	2.1 – 3.1 bard (30 – 45 psid)

** Maximum air/gas pressure for installation test is 6.2 barg (90 psig)


Part Number	描述
FTKSV404705	Filter Discs¹
FTKSV4047025	Filter Discs²

¹ Five discs per box, 2 Twenty-five discs per box


Part Number	Holder
FTK-200 Disc Holder	FTK-200

Further Equipment Recommended for Laboratory Testing


Part Number	Pressure Vessels (Stainless steel)
ZLK702G23LHKH4	Sealkleen™ vessel
Part Number	Accessories (Sealkleen Vessel)
GFX0290	Adapter 1 in.TC/Male Stäubli connector plug (3 mm) R ¹⁄₄ in.
GFX0390	Adapter 1 in.TC connector plug R ¹⁄₄ in.NPT (FTK-200 inlet fitting)
GFX0235	Male Stäubli connector plug (3 mm) R ¹⁄₄ in.
Part Number	Pressure Vessels (Disposable)
C3EP1	Novasip™ vessel
Part Number	Accessories (Novasip Vessel)
GFX0290	Adapter 1 in.TC/Male Stäubli connector plug (3 mm) R ¹⁄₄ in.
SLK1TC23H4	TC clamp + gasket silicone