The Mini Kleenpak capsules are compact filters used in the laboratory for volumes of 2 L to 50 L in process development, and in pilot and manufacturing scale operations if processing requirements do not demand a large filter.These filters are the smallest capsule filters in the UpScale™ Program range to utilize a pleated membrane, and are excellent for modelling filter performance at large production scale.
Key Features and Benefits
- Encapsulated format for higher flexibility, minimized cleaning and low installation costs
- Minimal hold up volume
- Ideal for upscale trials
- Hydrophilic polyethersulfone membrane for low adsorption and wide chemical compatibility
- Good wettability for a reliable integrity test
- Built-in, MachV asymmetric prefilter layer for long-life and low filtration costs
Quality Standards
- Manufactured for use in conformance with cGMP
- 100 % integrity tested
- ISO 9000 Certified Quality System
- Meets USP Biological Reactivity Test, in vivo, for Class VI-121 °C Plastics
- Every filter tested during manufacture.Test correlated to microbial retention
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Certificate of Test provided includes:
- Fabrication integrity
- Bacterial retention
- Materials of constructions
- Effluent quality for cleanliness, TOC and Water Conductivity, pH and Pyrogens
材料成分
| Filter Membrane | Hydrophilic PES |
| Support/Drainage | 聚丙烯 |
| 囊式过滤器 | 聚丙烯 |
| Filling Bell | 聚碳酸酯 |
| Sealing Technology | Thermal bonding without adhesives |
Operating Parameters(1)
| Maximum Temperature | 40 °C |
| 最大操作压力 | 4.1 bar (60 psi) at 40 °C |
| Maximum Differential Pressure | 4.1 bar (60 psi) at 40 °C |
(1) In compatible fluids which do not soften, swell or adversely affect the filter or its materials of construction
Sterilization(2)
| Autoclave | 3 x 60 minutes at 140 °C |
| Gamma Irradiation | Maximum of 50 kGy |
(2) Pre-sterilized Mini Kleenpak capsules must not be re-sterilized.Mini Kleenpak capsules must not be sterilized in-situ by passing steam under pressure.Water wet Supor EKV capsules prior to steaming to retain full water wettability for integrity testing
Typical Extractables in Water at 20 °C
| < 5.0 mg per capsule |
Nominal Dimensions
| Maximum diameter including valves | 53 mm (2.1 in.) |
| Length - Code 2 | 105 mm (4.1 in.) |
| Length - Code 8 | 73 mm (2.9 in.) |
Nominal Effective Filter Area (EFA)
| 220 cm² (0.24 ft²) |
Flow Characteristics
