Benchtop Tangential Flow Filtration at the Touch of a Button
The Minim II System, a benchtop Tangential Flow Filtration (TFF system), provides biotechnology and biopharmaceutical drug developers and manufacturers with the tools to optimize processes and minimize development times.The Minim II Tangential Flow Filtration system is an ideal instrument for running filterability at ultra-low volumes, since it allows users to accurately scale-up process conditions and maximize yields.
Using the Minim II system as a development tool, time, risk and expensive product volumes can all be minimized.
Sanitary Disposable Flowpath with Low Working Volumes
- Simplified System Setup - supplied with a color coded insert tray, sensors and connectors, to facilitate perfect alignment and installation of system components, every time
- Easy-fit Customized Single Use Tubing Kits - system hold-up and working volumes are minimized; risk of cross-contamination from tubing is eliminated
Graphical User Interface and Data Logging
User Friendly Interface
- Controls pump and stirrer speed; displays pressure in addition to pump speed, stirrer speed and system temperature
Ease of Data Collection
- To eliminate data recording and transcription errors, process parameters can be exported to a PC
Calibrated Instrumentation
- Pressure, temperature and pump speed calibration provides accuracy of data for critical process development
材料成分
Tubing (except pump tubing) | Polyvinylchloride |
Pressure Dome | 聚碳酸酯 |
Luer Fittings and Valves | 聚碳酸酯 |
Thermistor Housing | Polycarbonate with AISI 305 thermowell |
Vessel | Polysulfone with EPDM seal |
Pressure Pump Tubing | PharMed* BPT |
* PharMed is a trademark of Cole Palmer Instrument Co
Operating Conditions
操作压力 | 0 to 2.5 bar (0 to 36 psi) |
温度范围 | 0 °C to +25 °C |
流速 | 20 - 1100 mL/min |
Operating Volumes
Maximum Working Volume | 1¹ liter (nominal) |
Minimum Working Volume | 20 mL (separation device dependent) |
¹ 1 liter is the maximum batch volume.Larger volumes can be processed using a fed-batch approach
Physical Dimensions
Base Unit | W:320 mm x L 415 mm x H 150 mm (12.6 in. x L 16.3 in. x H 5.9 in.) |
Drip Tray | W:420 mm x L 280 mm x H 60 mm (16.5 in. x L 11.0 in. x H 2.4 in.) |
重量
Base Unit (including drip and insert tray) | 15 kg (33 lb) |
Centramate™ LV Cassette Holder | 4 kg (9 lb) |
Electrical Data
Voltage | 110 - 240 V AC |
Frequency | 50 / 60 Hz |
电源 | 200 W |
Communications Port | RS232 serial port |
Supplied Documentation
Quick Start Guide, Calibration Certificates, Final Inspection Certificate |
Supplied CD-ROM
Operating Instructions, CE Certificate, Pump Head User Guide, Data Logging Software, Data Logging Manual |
- Using three identical Minimate™ capsules, you can run the system with 150cm² effective filtration area
- Using three different Minimate™ capsules, you can determine the correct Molecular Weight Cut-Off (MWCO) for your application
订购须知 | Contents | Quantity | Part Number |
Minim II System* |
Includes packing case, Minim II base unit (including pump motor & stirrer base), thermistor cable assembly, |
1 |
M2BAS |
Feed/Retentate/Permeate* | Includes 6 sets of Feed, Retentate and Permeate kits |
1 |
M2KIT |
Vessel Kit* | Includes 6 sets of vessel, valves, tubing, syringe and vent filter |
1 |
M2VK |
Pump Tubing Kit* | Includes 6 x 2.5 bar (max) pump tubing sets |
1 |
M2TULP |
Minimate Capsule Kit | Includes 6 sets of tubing kits required to run 1, 2 or 3 Minimate™ capsules (capsules not included) |
1 |
M2MK |
文件材料 | Completed IQ/OQ, blank IQ/OQ & Validation Guide |
1 |
M2QUAL |
Centramate™ Cassette Holder | Includes cassette holder and torque wrench |
1 |
CM018LV |
*These items must be ordered to run the system.All other items are optional, to be ordered according to requirements