For Buffers, Tissue Culture Media,
and Other Biological Fluids
- Newer technology recommended for simplified scale-up
- High filtration area and compact size are ideal for upscale trials
- Minimal hold-up volume
- Good wettability for reliable integrity test
- Sealed membrane and housing uses fusion technology to eliminate potential extractables
- Gamma sterilized, non-pyrogenic, and provided with a removable filling bell (except sanitary flange option)
- Hydrophilic polyethersulfone membrane for low adsorption and wide chemical compatibility
- Very high flow rates and consistently higher total solution throughputs due to superior porosity over other membranes
- Designed to quickly process difficultto- filter solutions within 5-21 L, such as serum, serum-supplemented culture media, and ascites fluid
- Ideal in situations where rapid filtration or short processing times are essential
材料成分
- Filter Media:Supor EKV [hydrophilic polyethersulfone (PES)] membrane
- Housing, Vent Plug, and Support Material:聚丙烯
- Filling Bell:Polycarbonate (no filling bell on sanitary option)
- Sealing Technology:Thermal bonding without adhesives
孔径
- 0.2 微米
有效过滤面积
- 220 cm2
尺寸
- Housing Length:12094:10.5 cm (4.1 in.);12095:7.3 cm (2.9 in.)
- Housing Diameter:5.3 cm (2.1 in.) without vent, 6.7 cm (2.6 in.) with vent
Inlet/Outlet Connections
- 12094:6.4 - 12.7 mm (1/4 - 1/2 in.) stepped hose barb inlet and outlet
- 12095:13 mm (1/2 in.) sanitary flange inlet/outlet
Typical Hold-Up Volume (with 10 psi air purge)
- < 6 mL
Maximum Operating Temperature
- 60 °C (140 °F) at 2.1 bar (210 kPa, 30 psi)
最大操作压力
- 4.1 bar (410 kPa, 60 psi) at ambient temperature
Recommended Integrity Test Minimum Bubble Point - Water
- > 3.32 bar (332 kPa, 48 psi)
Typical Liquid Flow Rate
- 350 mL/min/0.1 bar (241 mL/min/psi)
Bacterial Retention
- Lot samples retain a minimum of 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision
Endotoxin Level
- < 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test
Biological Safety
- Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>
Sterilization
- Sterilized by gamma irradiation and individually packaged.If desired, autoclave once at 131 ºC (268 ºF) for 30 minutes.Water wet capsule prior to autoclaving.