Supor EKV filters are 0.2 micron rated validated sterilizing grade membranes.Ultiizing a laid-over-pleat membrane geometry for high flow rates and throughput performance, they are designed for the most cost effective filtration of a wide range of liquids such as buffers, tissue culture media, and others.A PES membrane ensures very high compatibility over the whole pH range plus very low protein binding to ensure the maximum transmission of active ingredients.
颇尔 的 AB 型过滤器是使用不锈钢滤壳组件的一次性滤芯，十分适合中等至大规模生产操作（100 L 至 >1000 L）。
A validation package for Supor grade EKV filters supports the assurance of safety within your process.
Key Features and Benefits
- Hydrophilic polyethersulfone membrane for low adsorption and wide chemical compatibility
- Good wettability for a reliable integrity test
- Patented Ultipleat® technology for high-area and good flow rates
- Built-in, MachV asymmetric prefilter layer for long-life and low filtration costs
- High-strength construction tolerates up to 1 bard (14.5 psid) differential pressure during steam-in-place sterilization
Quality Standards
- Manufactured for use in conformance with cGMP
- 100% integrity tested
- ISO 9000 Certified Quality System
- Meets USP Biological Reactivity Test, in vivo, for Class VI-121 °C Plastics
- Every filter tested during manufacture.Test correlated to microbial retention.
-
Certificate of Test provided includes:
- Fabrication Integrity
- Bacterial Retention
- Materials of constructions
- Effluent quality for cleanliness, TOC and Water Conductivity, pH and Pyrogens
Products in this datasheet may be covered by one or more patents including :
EP 1 096 983
US 6,739,459
材料成分
| Filter Membrane | Hydrophilic PES |
| Support/Drainage | 聚丙烯 |
| Core/End Caps | 聚丙烯 |
| Cage | Polypropylene with TiO2 (white colored) |
| O 型圈 | Silicone elastomer |
| Sealing Technology | Thermal bonding without adhesives |
Operating Parameters(1)
|
Maximum Differential Pressure (Forward Direction) |
5.5 bar (80 psi) at 40 °C 4.0 bar (58 psi) at 80 °C |
|
Maximum Differential Pressure (Reverse Direction) |
2.0 bar (30 psi) at 40 °C |
(1) In compatible fluids which do not soften, swell, or adversely affect the filter or its materials of construction
Sterilization(2)
| Autoclave | 30 x 60 minutes at 125°C, slow exhaust |
| In Situ Steam |
30 x 60 minutes at 125 °C 5 x 60 minutes at 142 °C |
(2) Water wet Supor EKV capsules prior to steaming to retain full water wettability for integrity testing
Typical Extractables in Water at 20 °C(3)
| < 25 mg after 4 hours extraction (per 254 mm module) |
(3) Tested on elements without pre-flushing
Integrity Test Values
| Values for 254 mm (10 inch) filter at 20°C | |
| Max. allowable Forward Flow (air test gas) | Water wet 17 mL/min at 2760 mbar (40 psi) |
Contact 颇尔 for multi-element integrity test values and recommended test procedures
Nominal Effective Filter Area (EFA) (4)
| 0.6 m² per 254 mm module (6.5 ft² per 10 in. module) |
| 0.26 m² per 125 mm module (2.8 ft² per 5 in. module) |
(4) 5 in. filters are standard pleated
Flow Characteristics
| 项目 | Nominal Length | Part Number |
| Supor® EX grade EKV Membrane Filter Cartridge 颇尔 Code 2 double O-ring (silicone elastomer), bayonet lock and flat top | 5 in. (125 mm) | AB05EKV2PH4 |
| Supor EX grade EKV Membrane Filter Cartridge 颇尔 Code 7 double O-ring (silicone elastomer), bayonet lock and fin | 10 in. (254 mm) | AB1EKV7PH4 |
| Supor EX grade EKV Membrane Filter Cartridge 颇尔 Code 7 double O-ring (silicone elastomer), bayonet lock and fin | 20 in. (508 mm) | AB2EKV7PH4 |
| Supor EX grade EKV Membrane Filter Cartridge 颇尔 Code 7 double O-ring (silicone elastomer), bayonet lock and fin | 30 in. (762 mm) | AB3EKV7PH4 |
| Supor EX grade EKV Membrane Filter Cartridge 颇尔 Code 7 double O-ring (silicone elastomer), bayonet lock and fin | 40 in. (1016 mm) | AB4EKV7PH4 |
