pall,颇尔,Ultipor VF 级 DV50 病毒清除过滤器滤芯,

pall,颇尔,Ultipor VF 级 DV50 病毒清除过滤器滤芯

Ultipor® VF Grade DV50 Virus Removal filter cartridges feature innovative hydrophilic PVDF microporous membranes to remove significant levels of viruses from biological solutions, while enabling > 95% transmission of proteins up to 300 kD or larger.Using patented Ultipleat® crescent-shaped pleated elements, the filters to incorporate 1.6 m² (17.5 ft²) of filter area per 10 in. (254 mm) element in standard single open-ended (SOE) AB sanitary style cartridges.Ultipor VF cartridges achieve practical flows and pressure drops while effectively removing nanometer-size viral contaminants with high protein yields.An optional sub-0.1 µm rated prefilter (Grade DVD) and Fluorodyne® II filters enhance throughputs and employ the same PVDF membrane material for ease of validation.Typical applications include purification of biopharmaceuticals, tissue and plasma derivatives, protein additives, culture media, diagnostic reagents, buffers and diluents.

特色及优点

Sanitary direct flow cartridges
6 log Titer Reduction (T_R) for 50 nm viruses (DV50 grade)
Robust size exclusion mechanism
PVDF microporous membranes
Narrow pore-size distribution
Inherently water wettable
Low binding for high protein yields
Very low extractables
Steamable in situ
100% integrity-tested
Individually serialized
Manufactured for use in conformance with cGMP
ISO 9000 Certified Quality System
Pharmaceutical P optimized
Certificate of Test provided
Validation Guide available
Discs and mini-cartridges (SBF Junior Style) available

Quality and Bio-Safety Biological Tests

Integrity
（正直诚信）

Every DV50 grade filter integrity tested during manufacture.Test correlated to viral (phage) retention.

Biological Tests

Meets USP Biological Reactivity Test, in vivo, for Class VI-121 °C Plastics

Effluent Quality Tests*

Meets Cleanliness per USP Particulates in Injectables
Non-Fiber-Releasing
Non-Pyrogenic per USP Bacterial

Endotoxins (< 0.25 EU/mL)

Meets Total Organic Carbon and Conductivity per USP Purified Water; pH per Sterile Purified Water

Autoclave Resistance

Lot samples multi-cycle autoclave challenged

* Per lot sample or rinse-flush aliquots

Products in this datasheet may be covered by one or more patents including :
EP 0 667 800
EP 0 982 061
EP 1 380 331
US 5,543,047
US 5,690,765
US 5,725,784
US 6,113,784
US 7,083,564
US 7,318,800
US 5,736,051

材料成分


膜	Hydrophilic modified polyvinylidenefluoride (PVDF)
Support and Drainage	聚酯
Core, Cage and End Caps	聚丙烯
Code 7 Adapter	Polypropylene with encapsulated stainless steel reinforcing ring for steaming in situ
O 型圈	Silicone¹

¹ Other polymers available

Removal Ratings


DVD	Sub-0.1 µm prefilter
DV50	T_R10⁶ for 50 nm viruses²

² Lot samples retain log 10⁶T_R of 53 nm spherical non-enveloped bacteriophage

Configuration (AB Code 7)

Double 226 O-ring adapters, fin end with bayonet lock

Nominal Dimensions


Lengths	10 in. (254 mm), 20 in. (508 mm), 30 in. (762 mm), 40 in. (1016 mm)
Diameter	70 mm (2.75 in.)

Nominal Filter Area³


DVD	0.9 m² (9.5 ft²)
UDV50	1.63 m² (17.5 ft²)

³ Per 10 in. (254 mm) element

Typical Flow Rate

Clear water flow is 1 L/min @ 2 bard (29 psid)

Operating Conditions*


Maximum Differential Pressure during Integrity Testing	6.0 bard (90 psid)
Maximum Differential Pressure for Continuous Service	3 bard (43.5 psid)
Recommended Operating ∆P	1-2 bard (15 – 29 psid)