
For Cost-Effective Filtration of Buffers, Tissue Culture Media, and Other Biological Solutions
- Newer technology recommended for simplified scale-up
- Disposable design reduces labor costs associated with assembling, cleaning, and testing stainless steel filter holders
- Encapsulated format for ease of use
- Extended life with built-in MachV asymmetric prefilter layer for maximum flow and throughput performance
- Low adsorption and high chemical compatibility with hydrophilic polyethersulfone membrane for high compatibility over the entire pH range and low protein binding
- Gamma-irradiated, non-pyrogenic, and non-cytotoxic
- Inherently hydrophilic for reliable integrity testing
-
Suitable for sterile filtration of a wide range of fluids, including:
- Buffers
- Biological fluids
- Cell culture media
- Ophthalmic products
材料成分
- Filter Media:Supor EKV [hydrophilic polyethersulfone (PES)] membrane
- Housing, Vent Plug, and Support Material:聚丙烯
- Filling Bell:Polycarbonate (no filling bell on sanitary flange option)
- Sealing Technology:Thermal bonding without adhesives
孔径
- 0.2 微米
有效过滤面积
- 400 Series:375 cm2
- 800 Series:750 cm2
- 1500 Series:1500 cm2
尺寸
- Housing Diameter (including valves):9.4 cm (3.7 in.)
-
400 Series Housing Length:
12460:11.7 cm (4.6 in.)
12461:15.7 cm (6.2 in.) -
800 Series Housing Length:
12463:15.7 cm (6.2 in.)
12464:19.7 cm (7.7 in.) -
1500 Series Housing Length:
12466:17.4 cm (6.8 in.)
12467:21.0 cm (8.3 in.)
Inlet/Outlet Connections
-
400 Series
12460:25 - 38 mm (1 - 1.5 in.) sanitary flange inlet/outlet connection
12461:13 mm (1/2 in.) hose barb inlet/outlet connection -
800 Series
12463:25 - 38 mm (1 - 1.5 in.) sanitary flange inlet/outlet connection
12464:13 mm (1/2 in.) hose barb inlet/outlet connection -
1500 Series
12466:25 - 38 mm (1 - 1.5 in.) sanitary flange inlet/outlet connection
12467:13 mm (1/2 in.) hose barb inlet/outlet connection
Maximum Operating Temperature
- 40 ºC (104 ºF) at 4.0 bar (400 kPa, 58 psi)
最大操作压力
- 5.2 bar (520 kPa, 75 psi) at 20 ºC (68 ºF)
Recommended Integrity Test Minimum Bubble Point - Water
- 3.32 bar (332 kPa, 48 psi) Typical Water Flow Rate
Typical Water Flow Rate
- 400 Series:700 mL/min/0.1 bar (483 mL/min/psi)
- 800 Series:1.5 L/min/0.1 bar (1.0 L/min/psi)
- 1500 Series:3.2 L/min/0.1 bar (2.2 L/min/psi)
Bacterial Retention
- Lot samples retain a minimum of 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision
Endotoxin Level
- < 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test
Biological Safety
- Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>
Sterilization
- Sterilized by gamma irradiation and individually packaged