Fast, Final Filtration and High Throughputs
for Liquid Volumes Up To 150 L
- Provides higher throughputs and faster flow rates than similarly-sized competitive devices
- Ideal for solutions requiring low protein binding
- Saves money by increasing throughput with available built-in prefilter
- 100% integrity testing assures sterile filtrate
- 0.1 μm Supor membrane version ensures sterile, mycoplasma-free cell culture media
- 熔焊部件可避免析出物从密封胶黏剂中释出
- Sterilization by gamma irradiation eliminates potential contamination by EtO residuals
- Large-volume media preparation
- Pilot-scale manufacturing
- Liquids requiring prefiltration, such as serum-containing media
- Sterile filtration of buffers
- Point-of-use filtration for laboratory water
- Reduce mycoplasma with the 0.1 µm pore size
材料成分
- Filter Media:Supor [hydrophilic polyethersulfone (PES)] membrane
- Housing, Vent Plug, and Filter Support:聚丙烯
- Sealing Technology:Thermal bonding
- Filling Bell:聚碳酸酯
孔径
- 0.1/0.1, 0.2/0.2, 0.8/0.2, and 0.8/0.45 μm
有效过滤面积
- 500 Series:500 cm2
- 1000 Series:1000 cm2
- 1500 Series:1500 cm2
尺寸
- Housing Diameter:6.9 cm (2.7 in.)
-
Overall Length (Without Filling Bell):
500 Series:14.5 cm (5.7 in.)
1000 Series:19.3 cm (7.6 in.)
1500 Series:22.9 cm (9.0 in.)
Inlet/Outlet Connections
- 500 and 1000 Series:6.4 - 12.7 mm (1/4 - 1/2 in.) stepped hose barb with filling bell on outlet
- 1500 Series:12.7 mm (1/2 in.) straight hose barb, no filling bell on outlet
Typical Hold-Up Volume (with 10 psi air purge)
- 500 Series:30 毫升
- 1000 Series:45 毫升
Maximum Operating Temperature
- 60 °C (140 °F) at 2.1 bar (210 kPa, 30 psi)
最大操作压力
- Continuous:4.1 bar (410 kPa, 60 psi) at ambient temperature
Recommended Integrity Test Minimum Bubble Point – Water
- 0.2 μm:3.5 bar (350 kPa, 51 psi)
- 0.45 μm:1.7 bar (170 kPa, 24 psi)
- 60% IPA/40% H2O (v:v)
- 0.1 μm:2.4 bar (240 kPa, 35 psi)
Typical Water Flow Rate
-
Lpm at 0.1 bar (10 kPa) [Lpm/psi]:
孔径 500 Sereis 1000 Sereis 1500 Series 0.1/0.1 µm 0.2 (0.2) 0.4 (0.3) - 0.2/0.2 µm 0.6 (0.4) 1.1 (0.8) 1.6 (1.1) 0.8/0.2 µm 1.1 (0.8) 1.6 (1.1) 2.2 (1.5) 0.8/0.45 µm 1.3 (0.9) 2.5 (1.7) -
Bacterial Retention
- 0.1/0.1 μm Capsules:Lot samples retain a minimum of 107 cfu/cm2 of A. laidlawii challenge per modified ASTM F838, current revision
- 0.2 μm Capsules:Lot samples retain a minimum of 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision
Endotoxin Level
- < 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test
Biological Safety
- Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>
Sterilization
- Sterilized by gamma irradiation
- If desired, autoclave once only prior to use at 121 - 123 °C (250 - 253 °F) for a maximum of 20 min.
Total Throughput Recorded for Devices with an EFA of Up to 1000 cm2
Throughput Determined using 3% TSB
Built-in Prefilter Enhances Total Throughput
Membrane Type:47 mm Disc
Throughput Determined using 2.5 % TSB