Fast, Final Filtration and High Throughputs
for Liquid Volumes Up To 150 L
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Provides higher throughputs and faster flow rates than similarly-sized competitive devices
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Ideal for solutions requiring low protein binding
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Saves money by increasing throughput with available built-in prefilter
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100% integrity testing assures sterile filtrate
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0.1 μm Supor membrane version ensures sterile, mycoplasma-free cell culture media
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熔焊部件可避免析出物从密封胶黏剂中释出
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Sterilization by gamma irradiation eliminates potential contamination by EtO residuals
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Large-volume media preparation
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Pilot-scale manufacturing
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Liquids requiring prefiltration, such as serum-containing media
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Sterile filtration of buffers
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Point-of-use filtration for laboratory water
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Reduce mycoplasma with the 0.1 µm pore size
材料成分
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Filter Media：Supor [hydrophilic polyethersulfone (PES)] membrane
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Housing, Vent Plug, and Filter Support:聚丙烯
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Sealing Technology:Thermal bonding
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Filling Bell:聚碳酸酯
孔径
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0.1/0.1, 0.2/0.2, 0.8/0.2, and 0.8/0.45 μm
有效过滤面积
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500 Series:500 cm2
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1000 Series:1000 cm2
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1500 Series:1500 cm2
尺寸
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Housing Diameter:6.9 cm (2.7 in.)
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Overall Length (Without Filling Bell):
500 Series:14.5 cm (5.7 in.)
1000 Series:19.3 cm (7.6 in.)
1500 Series:22.9 cm (9.0 in.)
Inlet/Outlet Connections
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500 and 1000 Series:6.4 - 12.7 mm (1/4 - 1/2 in.) stepped hose barb with filling bell on outlet
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1500 Series:12.7 mm (1/2 in.) straight hose barb, no filling bell on outlet
Typical Hold-Up Volume (with 10 psi air purge)
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500 Series:30 毫升
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1000 Series:45 毫升
Maximum Operating Temperature
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60 °C (140 °F) at 2.1 bar (210 kPa, 30 psi)
最大操作压力
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Continuous:4.1 bar (410 kPa, 60 psi) at ambient temperature
Recommended Integrity Test Minimum Bubble Point – Water
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0.2 μm:3.5 bar (350 kPa, 51 psi)
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0.45 μm:1.7 bar (170 kPa, 24 psi)
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60% IPA/40% H2O (v:v)
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0.1 μm:2.4 bar (240 kPa, 35 psi)
Typical Water Flow Rate
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Lpm at 0.1 bar (10 kPa) [Lpm/psi]:
|
|
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0.1/0.1 µm |
0.2 (0.2) |
0.4 (0.3) |
- |
|
0.2/0.2 µm |
0.6 (0.4) |
1.1 (0.8) |
1.6 (1.1) |
|
0.8/0.2 µm |
1.1 (0.8) |
1.6 (1.1) |
2.2 (1.5) |
|
0.8/0.45 µm |
1.3 (0.9) |
2.5 (1.7) |
- |
|
|
Bacterial Retention
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0.1/0.1 μm Capsules:Lot samples retain a minimum of 107 cfu/cm2 of A. laidlawii challenge per modified ASTM F838, current revision
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0.2 μm Capsules:Lot samples retain a minimum of 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision
Endotoxin Level
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< 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test
Biological Safety
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Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>
Sterilization
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Sterilized by gamma irradiation
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If desired, autoclave once only prior to use at 121 - 123 °C (250 - 253 °F) for a maximum of 20 min.
Total Throughput Recorded for Devices with an EFA of Up to 1000 cm2
Throughput Determined using 3% TSB
Built-in Prefilter Enhances Total Throughput
Membrane Type:47 mm Disc
Throughput Determined using 2.5 % TSB
