颇尔 Supor EKV filters are 0.2 micron-rated validated sterilizing grade membrane filters for cost effective filtration of a wide range of liquids such as buffers, tissue culture media and others.A PES membrane ensures very high compatibility over the whole pH range plus very low protein binding to ensure the maximum transmission of active ingredients.
Mini Kleenpak capsules are compact filters used in the laboratory for volumes of 2 L to 50 L in process development, and in pilot and manufacturing scale operations if processing requirements do not demand a large filter.These filters are the smallest capsule filters in 颇尔's UpScale™ Program range to utilize a pleated membrane, and are excellent for modelling filter performance at large production scale.
Key Features and Benefits
- Encapsulated format for higher flexibility, minimized cleaning and low installation costs
- Minimal hold up volume
- Ideal for upscale trials
- Hydrophilic polyethersulfone membrane for low adsorption and wide chemical compatibility
- Good wettability for a reliable integrity test
- Built-in, MachV asymmetric prefilter layer for long-life and low filtration costs
Quality Standards
- Manufactured for use in conformance with cGMP
- 100 % integrity tested
- ISO 9000 Certified Quality System
- Meets USP Biological Reactivity Test, in vivo, for Class VI-121 °C Plastics
- Every filter tested during manufacture.Test correlated to microbial retention
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Certificate of Test provided includes:
- Fabrication integrity
- Bacterial retention
- Materials of constructions
- Effluent quality for cleanliness, TOC and Water Conductivity, pH and Pyrogens
材料成分
Filter Membrane | Hydrophilic PES |
Support/Drainage | 聚丙烯 |
囊式过滤器 | 聚丙烯 |
Filling Bell | 聚碳酸酯 |
Sealing Technology | Thermal bonding without adhesives |
Operating Parameters(1)
Maximum Temperature | 40 °C |
最大操作压力 | 4.1 bar (60 psi) at 40 °C |
Maximum Differential Pressure | 4.1 bar (60 psi) at 40 °C |
(1) In compatible fluids which do not soften, swell or adversely affect the filter or its materials of construction
Sterilization(2)
Autoclave | 3 x 60 minutes at 140 °C |
Gamma Irradiation | Maximum of 50 kGy |
(2) Pre-sterilized Mini Kleenpak capsules must not be re-sterilized.Mini Kleenpak capsules must not be sterilized in-situ by passing steam under pressure.Water wet Supor EKV capsules prior to steaming to retain full water wettability for integrity testing
Typical Extractables in Water at 20 °C
< 5.0 mg per capsule |
Nominal Dimensions
Maximum diameter including valves | 53 mm (2.1 in.) |
Length - Code 2 | 105 mm (4.1 in.) |
Length - Code 8 | 73 mm (2.9 in.) |
Nominal Effective Filter Area (EFA)
220 cm² (0.24 ft²) |
Flow Characteristics